This spherical powder was created for military usage and is appropriate for the 5.56 NATO/223 Remington cartridge.
The 222 Remington and equivalent varmint cartridges have a variety of uses. Prairie dog shooters will love it, as J.B. Hodgdon has done for many years.
Never combine any two powders, regardless of their type, brand, or source.
Never use a smokeless powder in place of black powder or a substitute for black powder.